HIResist: Database of HIV-1 Resistance to Broadly Neutralizing Antibodies

About Us


HIResist is envisioned to be a comprehensive database of analysis and visualization tools designed to support the HIV-1 research community. Created by the Computational Biology Group in the Herschhorn Lab at the University of Minnesota, our mission is to provide user-friendly solutions that enable researchers to better understand the complexities of HIV-1 and accelerate scientific discovery.


Project funding

This project is supported by the Avenir Award (2019-2023) from the National Institute of Health/National Institute on Drug Abuse (NIH/NIDA).

NIDA's Avenir Awards are designed to stimulate innovation and potentially transformative research from early stage investigators. "Avenir" is the French word for "future" and these awards represent NIDA's commitment to supporting researchers who represent the future of addiction science.


Our Team


Alon Herschhorn, PhD

Dr. Herschhorn is an Associate Professor in the Division of Infectious Diseases and International Medicine at the University of Minnesota. Dr. Herschhorn received his PhD from Tel Aviv University in Israel, completed postdoctoral training at Dana-Farber Cancer Institute/Harvard Medical School (DFCI/HMS), and joined the DFCI/HMS faculty as instructor in Micrioblogy and Immunology in 2013. He uses interdisciplinary approaches at the interface of synthetic and molecualr virology, immunoloy and cell biology to develop a comprehensive research program for studying virus-host interactions at the molecular and cellular levels, with the aim of translating new insigts into novel therapies and vaccines to treat and prevent viral infections. Dr. Herschhorn's Avenir application is focused on delineating and targeting the pathways used by HIV to escape broadly neutralizing antibodies. More about Dr. Herschhorn.


Jeffy Jeffy

Jeffy is a Researcher in the Herschhorn Lab and currently works on the HIResist database and virology projects. She recieved her Bachelor's degree in Chemistry from the University of Minnesota in 2022 and is currently pursuing her Master's degree in Molecular Science and Software Engineering at the University of California, Berkeley.


Charis Liao

Charis is a Computer Scientist in the Herschhorn Lab working on the HIResist database. She also explored an Artificial Neural Network project related to the database. She recieved her Bachelor's degrees in Molecular and Cell Biology and Data Science from the University of California, Berkeley in 2022 and is currently pursuing her Master's degree Molecular Science and Software Engineering at the University of California, Berkeley.


Past Members

Milind Misra, PhD (8/2022 - 1/2024)

Milind led the Computational Biology Group in the Herschhorn Lab and managed the HIResist database project. After receiving his PhD from New Jersey Institute of Technology, he completed postdocs at University of Texas Medical Branch and Sandia National Laboratories and worked as a Senior Research Scientist at the University of New Mexico. His research experience spans diverse fields such as computer aided drug design, infectious disease, biodefense and green energy. Milind uses machine learning/AI algorithms to analyze diverse computational biology/chemistry data sets.